Direia 2025 Renewal (Updated): Stem Bio Complex®, Exosomes & Smart Delivery—Now in the UAE

Short on time? Direia’s renewed 2025 line brings Japanese beauty bioscience to skin that lives between desert heat and indoor A/C. Expect a smoother, bouncier, more luminous look—designed to layer easily into Middle East routines and lifestyles.

What’s new (at a glance)

• Proprietary Stem Bio Complex®: blends human stem cell conditioned culture medium with peptide vitamin C and NMN-family for firmer-looking, clearer skin.

• Exosome technology (cosmetic use): formulated to help disperse beneficial ingredients across the stratum corneum (outer skin layer).

• Innovative 3D Nanotechnology: elegant textures with delivery design inspired by medical-grade concepts.

• Minimalist, sustainable packaging: sophisticated gold/pearl accents; select eco-considered materials.

Why it suits skin in the UAE

• Daily A/C + strong sun → hydration feel that lasts and textures that don’t feel heavy.

• Pigmentation-prone climate → antioxidant support and brightening-focused actives.

• Event-ready culture → a bio-cellulose mask that delivers a “post-facial” glow in 20 minutes.

Hero products

1) Direia STM Serum iP Some (30 ml)

What it does:

• Visibly boosts firmness & elasticity

• Supports a more uniform, brighter look

• Layers smoothly under sunscreen and makeup

How to use:
AM: Cleanse → Serum (1–2 pumps) → Moisturizer → High-SPF
PM: Cleanse → Serum → Cream/Oil if needed

Who it’s for: All skin types, including sensitive-prone (patch test first).

2) Direia STM Mask iP Some (30 ml × 4)- coming soon

What it does:

• Bio-cellulose mask adheres closely for a dewy, translucent finish

• Perfect before occasions, photos, and evenings out

How to use:
Apply on clean skin for 15–20 minutes; pat in remaining essence; seal with cream.

Routine for the Middle East climate

1. AM: Gentle cleanse →DIreia Stem Lotion→ Direia STM Serum → Moisturizer → Broad-spectrum SPF 30+

2. PM: Cleanse →DIreia Stem Lotion→ Direia STM Serum → Cream/Oil (if needed)

3. Weekly boost: Direia STM Mask 1–2×

4. Lifestyle: Hydrate, limit midday sun, reapply SPF if outdoors

FAQs

What is Stem Bio Complex®?
Grazia’s proprietary blend featuring human stem cell culture fluid* plus peptide vitamin C & NMN derivatives—designed to support the look of firmness, elasticity and clarity.

What are exosomes in cosmetics?
Tiny extracellular vesicles formulated to help deliver beneficial ingredients across the stratum corneum for a smoother, revitalized appearance.

What is Innovative 3D Nanotechnology?
A delivery design that helps disperse actives across the outer skin layer for a refined, comfortable finish.

Penetration refers to delivery within the stratum corneum (outermost skin layer), not the living dermis.

Is this safe for sensitive skin?
The line is formulated with skin comfort in mind; always patch test first and introduce slowly.

Can I use it with retinoids or acids?

Yes, with sensible layering.

• Patch test first.

• Introduce slowly: If using retinol or strong acids (AHA/BHA/PHA), start the Direia serum on alternate nights.

• Avoid sandwiching with very low-pH acids in the same routine at first; build tolerance.

• Always use SPF in the morning.

• Sensitive or reactive skin: space actives out (e.g., acids one night, Direia serum the next; or retinol on separate nights).

• If irritation occurs, stop and consult a professional.

Pregnancy/breastfeeding?
Consult your healthcare provider before introducing new actives.

Key actives & why they matter

• Human Stem Cell Conditioned Culture Medium + Human Adipose-Derived Mesenchymal Cell Exosomes: cosmetic ingredients used to support a smoother, revitalized look.

• iPS Cell Conditioned Media (human hepatocyte-induced; immortalized human dental pulp stem cell medium): next-gen cosmetic ingredients informed by regenerative science.

• Peptides: Human Oligopeptide-1 (EGF), Oligopeptide-24, Oligopeptide-34, Human Oligopeptide-13, Human Oligopeptide-2, Palmitoyl Dipeptide-18, Ascorbyl-peptide (Ascorbyl Methylcarbonyl Pentapeptide-7) to help skin look firm, even, and refined.

• Antioxidants & Brightening: Ascorbic Acid, Dihydronicotinamide Riboside (niacinamide-family), Tocopheryl Acetate (Vitamin E).

• Moisture & Barrier: Sodium Hyaluronate, Phosphatidylcholine, Hydrogenated Lecithin, Caprylic/Capric Triglyceride.