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EGF (epidermal growth factor) is an advanced ingredient used in serums and ampoules formulated to support the look of smooth, refined, resilient skin. Popular in Korean and Japanese professional skincare, it's typically reserved for higher-investment routines focused on the visible signs of aging. EGF formulas are usually concentrated, so a little goes far — apply a small amount to clean skin before heavier products, and store as directed, since these ingredients can be sensitive to heat and light. It layers well with peptides and exosomes for a comprehensive anti-aging step. For skin showing loss of firmness and texture change, see our Mature Skin edit.